Mutation Introduction Mutation. Mutations are happening in our cells all the time, but almost none of these affect our health. This is very different than what we often see in science fiction in movies. In real life, a mutation is never so beneficial that it turns a person into a superhero or does something bizarre like cause them to grow wings. There are many reasons that mutations usually don't have major consequences. One reason is that our cells have very sophisticated machinery for repairing mutations very quickly. So there's not enough time for them to cause problems. Another is that most mutations occur in somatic cells like muscle cells or skin cells and can only affect the cell where the mutation occurred and cells that grow from that cell. Definition Mutation is the change in our DNA base pair sequence due to various environmental factors such as UV light, or mistakes during DNA replication. The DNA sequence is specific to each organism. It can sometimes undergo chan...